Effects of a human amniotic membrane extract on ARPE-19 cells.

ABSTRACT:

Background

Human Amniotic Membrane (hAM) is endowed with several biological activities and might be considered an optimal tool in surgical treatment for different ophthalmic pathologies. We pioneered the surgical use of hAM to treat retinal pathologies such as macular holes, tears, and retinal detachments, and to overcome photoreceptor damage in age-related macular degeneration. Although hAM contributed to improved outcomes, the mechanisms of its effects are not yet fully understood. The characterization and explanation of the effects of hAM would allow the adoption of this new natural product in different retinal pathologies, operative contexts, and hAM formulations. At this end, we studied the properties of a hAM extract (hAME) on the ARPE-19 cells.

Methods and results

A n

SUBMITTER: Lulli M 

PROVIDER: S-EPMC11178654 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature