A clade of receptor-like cytoplasmic kinases and 14-3-3 proteins coordinate inositol hexaphosphate accumulation.

ABSTRACT: Inositol hexaphosphate (InsP₆) is the major storage form of phosphorus in seeds. Reducing seed InsP₆ content is a breeding objective in agriculture, as InsP₆ negatively impacts animal nutrition and the environment. Nevertheless, how InsP₆ accumulation is regulated remains largely unknown. Here, we identify a clade of receptor-like cytoplasmic kinases (RLCKs), named Inositol Polyphosphate-related Cytoplasmic Kinases 1-6 (IPCK1-IPCK6), deeply involved in InsP₆ accumulation. The InsP₆ concentration is dramatically reduced in seeds of ipck quadruple (T-4m/C-4m) and quintuple (C-5m) mutants, accompanied with the obviously increase of phosphate (Pi) concentration. The plasma membrane-localized IPCKs recruit IPK1 involved in InsP

SUBMITTER: Xu LL 

PROVIDER: S-EPMC11178898 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature