The association of female reproductive factors with history of cardiovascular disease: a large cross-sectional study.

ABSTRACT:

Background

This study aimed to explore the association of female reproductive factors (age at first birth (AFB), age at last birth (ALB), number of pregnancies, and live births) with history of cardiovascular disease (CVD).

Methods

A total of 15,715 women aged 20 years or over from the National Health and Nutrition Examination Surveys from 1999 to 2018 were included in our analysis. Weighted multivariable logistic regression analysis and restricted cubic spline (RCS) model were used to evaluate the association of AFB and ALB with history of CVD in women. Additionally, the relationship between the number of pregnancies, and live births and history of CVD was also explored.

Results

After adjusting for potential confounding factors, the RCS plot showed a U-curve relation

SUBMITTER: Chen T 

PROVIDER: S-EPMC11181605 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature