Alternating Cystoscopy with Bladder EpiCheck^® in the Surveillance of Low-Grade Intermediate-Risk NMIBC: A Cost Comparison Model.

ABSTRACT:

Background

Bladder cancer surveillance is invasive, intensive and costly. Patients with low grade intermediate risk non-muscle invasive bladder cancer (NMIBC) are at high risk of recurrence.

Objective

The objective of this model is to compare the cost of a strategy to alternate surveillance with cystoscopy and a urine marker, Bladder EpiCheck, to standard surveillance.

Methods

A decision tree model was built using TreeAge Pro Healthcare to compare standard surveillance (Standard) with a modified surveillance incorporating Bladder EpiCheck. The model was based on 2 years of surveillance. Outcomes were obtained from literature. Costs were obtained from US and 9 European countries. Sensitivity analyses were performed.

Results

The efficacy of the model was equivale

SUBMITTER: Lotan Y 

PROVIDER: S-EPMC11181831 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature