Periodontal inflammatory and microbial profiles in healthy young African Americans and Caucasians.

ABSTRACT:

Aim

This study aimed to compare microbial and inflammatory profiles in periodontally/systemically healthy African American (AA) and Caucasian (C) individuals.

Materials and methods

Thirty-seven C and 46 AA aged from 5 to 25 years were evaluated regarding periodontal disease, caries, microbial subgingival profile via 16-s sequencing, as well as salivary and gingival crevicular fluid (GCF) inflammatory profile via multiplex assay.

Results

Greater probing depth percentage was detected in AA (p = .0075), while a higher percentage of caries index (p = .0069) and decayed, missing, filled teeth (DMFT) index (p = .0089) was observed in C, after adjusting for number of teeth, sex and age. Salivary levels of IL-6, IL-8 and TNFα were higher for C, whereas GCF levels of eotaxin,

SUBMITTER: Sabbagh S 

PROVIDER: S-EPMC11182714 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature