Advanced optical assessment and modeling of extrusion bioprinting.

ABSTRACT: In the context of tissue engineering, biofabrication techniques are employed to process cells in hydrogel-based matrices, known as bioinks, into complex 3D structures. The aim is the production of functional tissue models or even entire organs. The regenerative production of biological tissues adheres to a multitude of criteria that ultimately determine the maturation of a functional tissue. These criteria are of biological nature, such as the biomimetic spatial positioning of different cell types within a physiologically and mechanically suitable matrix, which enables tissue maturation. Furthermore, the processing, a combination of technical procedures and biological materials, has proven highly challenging since cells are sensitive to stress, for example from shear and tensile forces, wh

SUBMITTER: Lamberger Z 

PROVIDER: S-EPMC11183084 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature