Electronic Cigarettes vs Varenicline for Smoking Cessation in Adults: A Randomized Clinical Trial.

ABSTRACT:

Importance

Little is known about the relative effectiveness of nicotine-containing electronic cigarettes (ECs) compared with varenicline as smoking cessation aids.

Objective

To determine the relative effectiveness of ECs in smoking cessation.

Design, setting, and participants

This randomized placebo-controlled single-center trial was conducted in northern Finland. Participants aged 25 to 75 years who smoked daily and had volunteered to quit smoking were recruited from August 1, 2018, to February 20, 2020, via local media. The trial included 52 weeks of follow-up. All data analyses were conducted from September 1, 2022, to January 15, 2024. The participants, study nurses, and researchers were masked to group assignment.

Intervention

The participants were assigne

SUBMITTER: Tuisku A 

PROVIDER: S-EPMC11184496 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature