Distance-related functional reorganization predicts motor outcome in stroke patients.

ABSTRACT:

Background

Analyzing distance-dependent functional connectivity density (FCD) yields valuable insights into patterns of brain activity. Nevertheless, whether alterations of FCD in non-acute stroke patients are associated with the anatomical distance between brain regions remains unclear. This study aimed to explore the distance-related functional reorganization in non-acute stroke patients following left and right hemisphere subcortical lesions, and its relationship with clinical assessments.

Methods

In this study, we used resting-state fMRI to calculate distance-dependent (i.e., short- and long-range) FCD in 25 left subcortical stroke (LSS) patients, 22 right subcortical stroke (RSS) patients, and 39 well-matched healthy controls (HCs). Then, we compared FCD differences amo

SUBMITTER: Hong W 

PROVIDER: S-EPMC11184708 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature