Measurement of glomerular filtration rate in cats: methods and advantages over routine markers of renal function.

ABSTRACT:

Practical relevance

Routinely used markers of renal function in clinical practice include urea and creatinine. However, these are insensitive markers, particularly in the early stages of kidney disease. Measurement of glomerular filtration rate (GFR) is regarded as the most sensitive index of functioning renal mass. It may be useful for feline patients in varying clinical scenarios; for example, where a more accurate measurement of renal function may aid diagnosis, to enable response to therapeutic interventions to be more closely monitored, or to evaluate renal function prior to the use of nephrotoxic or renally cleared drugs.

Clinical challenges

Traditional methods of measuring GFR, such as renal clearance or multisample plasma clearance techniques, are generally impractic

SUBMITTER: Finch N 

PROVIDER: S-EPMC11185244 | biostudies-literature | 2014 Sep

REPOSITORIES: biostudies-literature