Complete spatiotemporal quantification of cardiac motion in mice through enhanced acquisition and super-resolution reconstruction.

ABSTRACT: The quantification of cardiac motion using cardiac magnetic resonance imaging (CMR) has shown promise as an early-stage marker for cardiovascular diseases. Despite the growing popularity of CMR-based myocardial strain calculations, measures of complete spatiotemporal strains (i.e., three-dimensional strains over the cardiac cycle) remain elusive. Complete spatiotemporal strain calculations are primarily hampered by poor spatial resolution, with the rapid motion of the cardiac wall also challenging the reproducibility of such strains. We hypothesize that a super-resolution reconstruction (SRR) framework that leverages combined image acquisitions at multiple orientations will enhance the reproducibility of complete spatiotemporal strain estimation. Two sets of CMR acquisitions were obtained

SUBMITTER: Mukherjee T 

PROVIDER: S-EPMC11185553 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature