Neural basis of cognitive control signals in anterior cingulate cortex during delay discounting.

ABSTRACT: Cognitive control involves allocating cognitive effort according to internal needs and task demands and the Anterior Cingulate Cortex (ACC) is hypothesized to play a central role in this process. We investigated the neural basis of cognitive control in the ACC of rats performing an adjusting-amount delay discounting task. Decision-making in this this task can be guided by using either a lever-value tracking strategy, requiring a 'resource-based' form of cognitive effort or a lever-biased strategy requiring a 'resistance-based' form of cognitive effort. We found that ACC ensembles always tightly tracked lever value on each trial, indicative of a resource-based control signal. These signals were prevalent in the neural recordings and were influenced by the delay. A shorter delay was associat

SUBMITTER: Seamans JK 

PROVIDER: S-EPMC11185781 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature