Increased triacylglycerol production in Rhodococcus opacus by overexpressing transcriptional regulators.

ABSTRACT: Lignocellulosic biomass is currently underutilized, but it offers promise as a resource for the generation of commercial end-products, such as biofuels, detergents, and other oleochemicals. Rhodococcus opacus PD630 is an oleaginous, Gram-positive bacterium with an exceptional ability to utilize recalcitrant aromatic lignin breakdown products to produce lipid molecules such as triacylglycerols (TAGs), which are an important biofuel precursor. Lipid carbon storage molecules accumulate only under growth-limiting low nitrogen conditions, representing a significant challenge toward using bacterial biorefineries for fuel precursor production. In this work, we screened overexpression of 27 native transcriptional regulators for their abilities to improve lipid accumulation under nitrogen-rich cond

SUBMITTER: Anthony WE 

PROVIDER: S-EPMC11186279 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature