The feasibility and acceptability of collecting psychosocial outcome measures embedded within a precision medicine trial for childhood cancer.

ABSTRACT:

Background

Patient-reported outcomes measures (PROMs) are increasingly being collected within cancer clinical trials, yet limited literature on the feasibility and acceptability of doing so.

Methods

We collected parent-proxy and adolescent (≥12 years old) PROMs through a longitudinal, psychosocial sub-study ('PRISM-Impact') embedded in a precision medicine trial for children with poor prognosis cancer ('PRISM'). We report on feasibility (response, participation, and attrition rates; follow-up and responding to elevated distress) and acceptability (parents' perceived benefit/burden of participation; and impact on decision to participate in PRISM) of PRISM-Impact.

Results

Over the reporting period, 462 families were eligible for PRISM-Impact. Family and adolescent respo

SUBMITTER: Robertson EG 

PROVIDER: S-EPMC11187165 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature