Long-term seizure diary tracking habits in clinical studies: Evidence from the Human Epilepsy Project.

ABSTRACT:

Objective

To characterize seizure tracking patterns of people with focal epilepsy using electronic seizure diary entries, and to assess for risk factors associated with poor tracking.

Methods

We analyzed electronic seizure diary data from 410 participants with newly diagnosed focal epilepsy in the Human Epilepsy Project 1 (HEP1). Each participant was expected to record data each day during the study, regardless of seizure occurrence. The primary outcome of this post-hoc analysis was whether each participant properly tracked a seizure diary entry each day during their study participation. Using finite mixture modeling, we grouped patient tracking trajectories into data-driven clusters. Once defined, we used multinomial modeling to test for independent risk factors of tracking

SUBMITTER: Miller KR 

PROVIDER: S-EPMC11189103 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature