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A sensitivity analysis for temporal bias in cross-sectional mediation.


ABSTRACT: For over three decades, methodologists have cautioned against the use of cross-sectional mediation analyses because they yield biased parameter estimates. Yet, cross-sectional mediation models persist in practice and sometimes represent the only analytic option. We propose a sensitivity analysis procedure to encourage a more principled use of cross-sectional mediation analysis, drawing inspiration from Gollob and Reichardt (1987, 1991). The procedure is based on the two-wave longitudinal mediation model and uses phantom variables for the baseline data. After a researcher provides ranges of possible values for cross-lagged, autoregressive, and baseline Y and M correlations among the phantom and observed variables, they can use the sensitivity analysis to identify longitudinal

SUBMITTER: Georgeson AR 

PROVIDER: S-EPMC11190060 | biostudies-literature | 2025 Dec

REPOSITORIES: biostudies-literature