Laparoscopic versus open surgery in treating patients with gallbladder cancer: a systematic review and meta-analysis.

ABSTRACT:

Background

Concerns over the security of laparoscopic radical operation for gallbladder cancer (GBC) persist. This systematic review and meta-analysis attempted to compare the safety and efficacy of laparoscopic surgery (LS) versus open surgery (OS) in the treatment of GBC.

Methods

The PubMed, EMBASE, and Web of Science were searched from inception to July 18, 2022. Literature search, quality assessment, and data extraction were completed independently and in duplicate. Effect-size estimates expressed as weighted mean difference (WMD) or odds ratio (OR) with 95% confidence interval (CI) were derived under the random-effects model.

Results

A total of 27 independent studies including 2,868 participants were meta-analyzed. Significance was noted for intraoperative blood

SUBMITTER: Li D 

PROVIDER: S-EPMC11190509 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature