Interobserver variation in tumor delineation of liver metastases using Magnetic Resonance Imaging.

ABSTRACT:

Background and purpose

Magnetic Resonance Imaging (MRI) guided stereotactic body radiotherapy (SBRT) of liver metastases is an upcoming high-precision non-invasive treatment. Interobserver variation (IOV) in tumor delineation, however, remains a relevant uncertainty for planning target volume (PTV) margins. The aims of this study were to quantify IOV in MRI-based delineation of the gross tumor volume (GTV) of liver metastases and to detect patient-specific factors influencing IOV.

Materials and methods

A total of 22 patients with liver metastases from three primary tumor origins were selected (colorectal(8), breast(6), lung(8)). Delineation guidelines and planning MRI-scans were provided to eight radiation oncologists who delineated all GTVs. All delineations were centrally

SUBMITTER: Peltenburg JE 

PROVIDER: S-EPMC11190710 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature