Simulation-based economic evaluation of the Wolbachia method in Brazil: a cost-effective strategy for dengue control.

ABSTRACT:

Background

Dengue virus (DENV) is an arbovirus transmitted by Aedes aegypti mosquitoes, which can cause severe conditions such as hemorrhagic fever and dengue shock syndrome. These conditions are associated with adverse social, clinical, and economic consequences in Brazil. Herein, the Wolbachia mosquito replacement method is a promising dengue control strategy.

Methods

We estimated the economic impact of implementing the Wolbachia mosquito replacement method in seven Brazilian cities. A mathematical microsimulation model tracked nearly 23 million inhabitants over a 20-year period, considering the transitions between five different health states (susceptible, inapparent, outpatient, hospitalised and death). Direct costs included local dengue control programs, W

SUBMITTER: Zimmermann IR 

PROVIDER: S-EPMC11190723 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature