Effect of probiotics on children with autism spectrum disorders: a meta-analysis.

ABSTRACT:

Background

Researches have found that alteration of intestinal flora may be closely related to the development of autism spectrum disorder (ASD). However, whether probiotics supplementation has a protective effect on ASD remains controversial. This meta-analysis aimed to analyze the outcome of probiotics in the treatment of ASD children.

Methods

The Pubmed, Cochrane Library, Web of Science and Embase were searched until Sep 2022. Randomized controlled trials (RCTs) relevant to the probiotics and placebo treatment on ASD children were screened. Quality assessment of the included RCTs was evaluated by the Cochrane collaboration's tool. The primary outcomes were ASD assessment scales, including ABC (aberrant behavior checklist) and CBCL (child behavior checklist) for evaluating

SUBMITTER: Zeng P 

PROVIDER: S-EPMC11191217 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature