Association Between Oral Malodor and Dementia: An 11-Year Follow-Up Study in Japan.

ABSTRACT:

Background

As infrequent social interaction is a potential risk of dementia, oral malodor may increase the risk of dementia, including Alzheimer's disease.

Objective

This study investigated the association between malodor and dementia.

Methods

We used the Japan Public Health Center-based Prospective Study data obtained at Yokote City. A total of 1,493 individuals aged 56 to 75 years underwent a dental examination and self-reported survey from May 2005 to January 2006. Follow-up for the onset of dementia was conducted using long-term care insurance data from 2006 to 2016. Hazard ratios of oral malodor on dementia were estimated by the Cox proportional hazards model. The inverse probability-weighted Cox model was used as a sensitivity analysis.

Results

The study

SUBMITTER: Ho DSM 

PROVIDER: S-EPMC11191629 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature