Effectiveness of Simultaneous Combined Intervention for Enhancing Cognitive Function in Patients with Moderate Alzheimer's Disease.

ABSTRACT:

Background

The evidence supporting the effectiveness of combined interventions in Alzheimer's disease (AD) patients remains inconclusive.

Objective

The aim of this study was to evaluate the mid- and long-term effectiveness of physical training, alone or combined with cognitive games, on cognitive performance in patients with moderate AD.

Methods

Seventy-nine AD patients (≈73% females, age of ≈70±1 years) were randomly divided into three groups: aerobic-based training (AT-group, n = 27), aerobic-based training plus cognitive games (ACT-group, n = 25), and a control group engaged in reading (CG, n = 26), two sessions per week. Cognitive performance was evaluated at the start, 4th week (W4), end of the 8th week (W8), and after a 4-week detraining per

SUBMITTER: Ben Ayed I 

PROVIDER: S-EPMC11191630 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature