Risk-reducing salpingo-oophorectomy among diverse patients with BRCA mutations at an urban public hospital: a mixed methods study.

ABSTRACT:

Objectives

To assess the association of socioeconomic demographics with recommendation for and uptake of risk-reducing bilateral salpingo-oophorectomy (rrBSO) in patients with BRCA1 and BRCA2 (BRCA1/2) mutations.

Design

Retrospective cohort, semistructured qualitative interviews.

Setting and participants

BRCA1/2 mutation carriers at an urban, public hospital with a racially and socioeconomically diverse population.

Intervention

None.

Primary and secondary outcomes

The primary outcomes were rate of rrBSO recommendation and completion. Secondary outcomes were sociodemographic variables associated with rrBSO completion.

Results

The cohort included 167 patients with BRCA1/2 mutations of whom 39% identified as black (

SUBMITTER: Lamacki AJ 

PROVIDER: S-EPMC11191783 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature