The Impact of Donor Body Mass Index on Safety and Outcomes in Living Donor Liver Transplantation: An Analysis of the National United States Database.

ABSTRACT:

Background

The prevalence of obesity is rising in the general population. Donor obesity (body mass index ≥30 kg/m²) may potentially reduce the donor pool and impact outcomes in living donor liver transplantation (LDLT).

Methods

We utilized the national transplant database to investigate the impact of donor obesity on donor and recipient outcomes. This was a retrospective cohort study of all LDLTs performed in the United States between January 2010 and June 2023. Outcomes of interest were analyzed by univariable and multivariable logistic regression. Patient and graft survival was evaluated using Kaplan-Meier and Cox proportional analysis.

Results

Six hundred seventy-four donors with obesity and 3498 donors without obesity were analyzed. Donors with obesity

SUBMITTER: Banker A 

PROVIDER: S-EPMC11191960 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature