Use and Outcomes of Dexamethasone in the Management of Malignant Small Bowel Obstruction.

ABSTRACT:

Objective

To describe rates of dexamethasone use in the nonoperative management of malignant small bowel obstruction (mSBO) and their outcomes.

Background

mSBO is common in patients with advanced abdominal-pelvic cancers. Management includes prioritizing quality of life and avoiding surgical intervention when possible. The use of dexamethasone to restore bowel function is recommended in the National Comprehensive Cancer Network guidelines for mSBO. Yet, it is unknown how often dexamethasone is used for mSBO and whether results from nonresearch settings support its use.

Methods

This is a multicenter retrospective cohort study including unique admissions for mSBO from January 1, 2019 to December 31, 2021. Dexamethasone use and management outcomes were summarized with de

SUBMITTER: Yang FF 

PROVIDER: S-EPMC11191995 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature