Generalizability of Randomized Clinical Trial Outcomes for Diabetes Control Resulting From Bariatric Surgery.

ABSTRACT:

Objective

To assess the external validity of randomized controlled trials (RCTs) of bariatric surgical treatment on diabetes control.

Background

Multisite RCTs provide the strongest evidence supporting clinical treatments and have the greatest internal validity. However, characteristics of trial participants may not be representative of patients receiving treatment in the real world. There is a need to assess how the results of RCTs generalize to all contemporary patient populations undergoing treatments.

Methods

All patients undergoing sleeve gastrectomy at University of California Los Angeles (UCLA) between January 8, 2018 and May 19, 2023 had their baseline characteristics, weight change, and diabetes control compared with those enrolled in the surgical treatment a

SUBMITTER: Livingston EH 

PROVIDER: S-EPMC11192007 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature