Highly pathogenic avian influenza A(H5N1) in animals: A systematic review and meta-analysis.

ABSTRACT:

Introduction

Avian influenza A H5N1 is a significant global public health threat. Although relevant, systematic reviews about its prevalence in animals are lacking.

Methods

We performed a systematic literature review in bibliographic databases to assess the prevalence of H5N1 in animals. A meta-analysis with a random-effects model was performed to calculate the pooled prevalence and 95 % confidence intervals (95%CI). In addition, measures of heterogeneity (Cochran's Q statistic and I² test) were reported.

Results

The literature search yielded 1359 articles, of which 33 studies were fully valid for analysis, including 96,909 animals. The pooled prevalence for H5N1 in birds (n = 90,045, 24 studies) was 5.0 % (95%CI: 4.0-6.0 %; I² = 99.21); in pigs

SUBMITTER: Bonilla-Aldana DK 

PROVIDER: S-EPMC11192795 | biostudies-literature | 2024 Aug-Oct

REPOSITORIES: biostudies-literature