Antiplatelet Resistance in Coronary Artery Bypass Grafting: A Systematic Review.

ABSTRACT:

Background

This systematic review examines the occurrence and implications of resistance to primary antiplatelet agents, aspirin and clopidogrel, often utilised in patients undergoing coronary artery bypass grafting (CABG), alongside the methodologies for assessment of such resistance.

Methods

An extensive literature search across various databases such as PubMed, MEDLINE via Ovid, Embase, and Cochrane CENTRAL until May 2024 was conducted to identify studies evaluating antiplatelet resistance in on-pump and off-pump CABG patients. Following quality assessment, only high-quality studies were incorporated into this review.

Results

This review included 19 studies with 3,915 patients, four of which were randomised controlled trials and 15 were observational studies. Aspir

SUBMITTER: Thet MS 

PROVIDER: S-EPMC11193597 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature