RNF213 Variants, Vasospastic Angina, and Risk of Fatal Myocardial Infarction.

ABSTRACT:

Importance

Vasospastic angina (VSA) is vasospasm of the coronary artery and is particularly prevalent in East Asian populations. However, the specific genetic architecture for VSA at genome-wide levels is not fully understood.

Objective

To identify genetic factors associated with VSA.

Design, setting, and participants

This was a case-control genome-wide association study of VSA. Data from Biobank Japan (BBJ; enrolled patients from 2002-2008 and 2013-2018) were used, and controls without coronary artery disease (CAD) were enrolled. Patients from the BBJ were genotyped using arrays or a set of arrays. Patients recruited between 2002 and 2005 were classified within the first dataset, and those recruited between 2006 and 2008 were classified within the second dataset. To

SUBMITTER: Hikino K 

PROVIDER: S-EPMC11195602 | biostudies-literature | 2024 Aug

REPOSITORIES: biostudies-literature