Left ventricular strain-volume loops in bicuspid aortic valve disease: new insights in cardiomechanics.

ABSTRACT:

Aims

By combining temporal changes in left ventricular (LV) global longitudinal strain (GLS) with LV volume, LV strain-volume loops can assess cardiac function across the cardiac cycle. This study compared LV strain-volume loops between bicuspid aortic valve (BAV) patients and controls, and investigated the loop's prognostic value for clinical events.

Methods and results

From a prospective cohort of congenital heart disease patients, BAV patients were selected and compared with healthy volunteers, who were matched for age and sex at group level. GLS analysis from apical views was used to construct strain-volume loops. Associations with clinical events, i.e. a composite of all-cause mortality, heart failure, arrhythmias, and aortic valve replacement, were assessed by Cox regr

SUBMITTER: Keuning ZA 

PROVIDER: S-EPMC11195802 | biostudies-literature | 2024 Apr

REPOSITORIES: biostudies-literature