The role of miR-143/miR-145 in the development, diagnosis, and treatment of diabetes.

ABSTRACT:

Objectives

Diabetes mellitus [DM], is a multifaceted metabolic disease, which has become a worldwide threat to human wellness. Over the past decades, an enormous amount of attention has been devoted to understanding how microRNAs [miRNAs], a class of small non-coding RNA regulators of gene expression at the post-transcriptional level, are tied to DM pathology. It has been demonstrated that miRNAs control insulin synthesis, secretion, and activity. This review aims to provide an evaluation of the use of miR-143 and miR-145 as biomarkers for the diagnosis and prognosis of diabetes.

Methods

The use of miR-143 and miR-145 as biomarkers for the diagnosis and prognosis of diabetes has been studied, and research that examined this link was sought after in the literature. In additio

SUBMITTER: Rasmi Y 

PROVIDER: S-EPMC11196424 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature