Insulin resistance-related circulating predictive markers in the metabolic syndrome: a systematic review in the Iranian population.

ABSTRACT:

Background

Specific biomarkers for metabolic syndrome (MetS) may improve diagnostic specificity for clinical information. One of the main pathophysiological mechanisms of MetS is insulin resistance (IR). This systematic review aimed to summarize IR-related biomarkers that predict MetS and have been investigated in Iranian populations.

Methods

An electronic literature search was done using the PubMed and Scopus databases up to June 2022. The risk of bias was assessed for the selected articles using the instrument suggested by the Joanna Briggs Institute (JBI). This systematic review protocol was registered with PROSPERO (registration number CRD42022372415).

Results

Among the reviewed articles, 46 studies investigated the association between IR biomarkers and MetS in th

SUBMITTER: Zahedi AS 

PROVIDER: S-EPMC11196549 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature