Metabolic syndrome as a risk factor for the development of kidney dysfunction: a meta-analysis of observational cohort studies.

ABSTRACT:

Background

Chronic kidney disease (CKD) is a major global health concern with increasing prevalence and associated complications. Metabolic syndrome (MetS) has been linked to CKD, but the evidence remains inconsistent. We conducted a systematic review and meta-analysis to investigate the association between MetS and kidney dysfunction.

Method

We conducted a comprehensive search of databases until December 2022 for cohort studies assessing the association between MetS and incident kidney dysfunction. Meta-analysis was performed using fixed and random effects models. Subgroup analyses were conducted to explore heterogeneity. Publication bias was assessed using Egger's and Begg's tests.

Result

A total of 24 eligible studies, involving 6,573,911 participants, were include

SUBMITTER: Valizadeh A 

PROVIDER: S-EPMC11196551 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature