Apolipoprotein A-I levels in the survival of patients with colorectal cancer: a retrospective study.

ABSTRACT:

Background

Abnormal lipid levels have been associated with cancer incidence and progression. However, limited studies have investigated the relationship between apolipoprotein A-I (ApoA-I) and colorectal cancer (CRC). This study assessed the significance of ApoA-I levels in progression-free survival (PFS) and overall survival (OS) of patients with CRC.

Methods

Survival curves were compared using Kaplan-Meier analysis, while the predictive values of various lipid indicators in CRC prognosis were evaluated based on receiver operating characteristic curves. The factors influencing PFS and OS in patients with CRC were analyzed using Cox proportional hazards regression models. Finally, the relationship between ApoA-I level and disease recurrence was investigated through logistic

SUBMITTER: Xie H 

PROVIDER: S-EPMC11196595 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature