Increased biofilm formation in dual-strain compared to single-strain communities of Cutibacterium acnes.

ABSTRACT: Cutibacterium acnes is a known opportunistic pathogen in orthopedic implant-associated infections (OIAIs). The species of C. acnes comprises distinct phylotypes. Previous studies suggested that C. acnes can cause single- as well as multi-typic infections, i.e. infections caused by multiple strains of different phylotypes. However, it is not known if different C. acnes phylotypes are organized in a complex biofilm community, which could constitute a multicellular strategy to increase biofilm strength and persistency. Here, the interactions of two C. acnes strains belonging to phylotypes IB and II were determined in co-culture experiments. No adverse interactions between the strains were observed in liquid culture or on agar plates; instead, biofilm formation in both microtiter plates and on

SUBMITTER: Bjerg CSB 

PROVIDER: S-EPMC11196685 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature