Correlation between normally aerated lung and respiratory system compliance at clinical high positive end-expiratory pressure in patients with COVID-19.

ABSTRACT: Normally aerated lung tissue on computed tomography (CT) is correlated with static respiratory system compliance (C_rs) at zero end-expiratory pressure. In clinical practice, however, patients with acute respiratory failure are often managed using elevated PEEP levels. No study has validated the relationship between lung volume and tissue and C_rs at the applied positive end-expiratory pressure (PEEP). Therefore, this study aimed to demonstrate the relationship between lung volume and tissue on CT and C_rs during the application of PEEP for the clinical management of patients with acute respiratory distress syndrome due to COVID-19. Additionally, as a secondary outcome, the study aimed to evaluate the relationship between CT characteristics and C_rs,

SUBMITTER: Ogura K 

PROVIDER: S-EPMC11196724 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature