CT-determined low skeletal muscle index predicts poor prognosis in patients with colorectal cancer.

ABSTRACT:

Background

Sarcopenia is highly prevalent among patients with colorectal cancer (CRC). Computed tomography (CT)-based assessment of low skeletal muscle index (SMI) is widely used for diagnosing sarcopenia. However, there are conflicting findings on the association between low SMI and overall survival (OS) in CRC patients. The objective of this study was to investigate whether CT-determined low SMI can serve as a valuable prognostic factor in CRC.

Methods

We collected data from patients with CRC who underwent radical surgery at our institution between June 2020 and November 2021. The SMI at the third lumbar vertebra was calculated using CT scans, and the cutoff values for defining low SMI were determined using receiver operating characteristic curves. Univariate and multivari

SUBMITTER: Feng Y 

PROVIDER: S-EPMC11196831 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature