Waist-to-height ratio and body fat percentage as risk factors for ischemic cardiovascular disease: a prospective cohort study from UK Biobank.

ABSTRACT:

Background

The independent effect of waist-to-height ratio (WHtR) and body fat percentage (BF%) on ischemic cardiovascular disease (CVD) remains uncertain.

Objectives

This study aimed to investigate the independent associations of WHtR and BF% with ischemic CVD.

Methods

This prospective cohort study used data from the UK Biobank. BF% was calculated as fat mass divided by body weight, measured by bioimpedance. Cox models estimated hazard ratios (HRs) with 95% confidence intervals (CIs) for overall and sex-specific associations of BF% and WHtR with risks of ischemic CVD and its main subtypes [myocardial infarction (MI) and ischemic stroke (IS)], adjusted for a range of potential confounders, including mutual adjustment for BF% and WHtR.

Results

In total, 468,333

SUBMITTER: Feng Q 

PROVIDER: S-EPMC11196863 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature