Causal associations between pediatric asthma and united airways disease: a two-sample Mendelian randomization analysis.

ABSTRACT:

Background

Prior observational research has indicated a potential link between pediatric asthma and united airways disease (UAD). However, these findings could be subject to confounding factors and reverse causation. Therefore, our study utilizes Mendelian randomization (MR) method to further investigate the causal relationship between pediatric asthma and UAD.

Methods

We conducted a comprehensive two-sample Mendelian randomization (MR) analysis to investigate the association between pediatric asthma and seven groups of UAD, including chronic sinusitis, chronic rhinitis, nasopharyngitis and pharyngitis, chronic diseases of tonsils and adenoids, chronic laryngitis and laryngotracheitis, chronic bronchitis, bronchiectasis, chronic obstructive pulmonary disease (COPD). The pres

SUBMITTER: Gao T 

PROVIDER: S-EPMC11196945 | biostudies-literature | 2024

REPOSITORIES: biostudies-literature