Precision medicine in Asia enhanced by next-generation sequencing: Implications for Thailand through a scoping review and interview study.

ABSTRACT: Next-generation sequencing (NGS) significantly enhances precision medicine (PM) by offering personalized approaches to diagnosis, treatment, and prevention of unmet medical needs. Little is known about the current situation of PM in Asia. Thus, we aimed to conduct an overview of the progress and gaps in PM in Asia and enrich it with in-depth insight into the possibilities of future PM in Thailand. This scoping review focused on Asian countries starting with non-cancer studies, including rare and undiagnosed diseases (RUDs), non-communicable diseases (NCDs), infectious diseases (IDs), and pharmacogenomics, with a focus on NGS. Subsequent in-depth interviews with experts in Thailand were performed, and a thematic analysis served as the main qualitative methodology. Out of 2898 searched artic

SUBMITTER: Phanthunane C 

PROVIDER: S-EPMC11197108 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature