Associations between admission levels of multiple biomarkers and subsequent worse outcomes in acute ischemic stroke patients.

ABSTRACT: The modified Rankin Scale change score (ΔmRS) is useful for evaluating acute poststroke functional improvement or deterioration. We investigated the relationship between multiple biomarkers and ΔmRS by analyzing data on 6931 patients with acute ischemic stroke (average age 62.3 ± 11.3 years, 2174 (31.4%) female) enrolled from the Third China National Stroke Registry (CNSR-III) and 15 available biomarkers. Worse outcomes at 3 months were defined as ΔmRS_3m-discharge ≥1 (ΔmRS_3m-discharge = mRS_3m-mRS_discharge). Adjusted odds ratios (aORs) and their 95% confidence intervals (CIs) were calculated from logistic regression models. At 3-months poststroke, 1026 (14.8%) patients experienced worse outcomes. The highest quartiles of white blood cells (WBCs) (

SUBMITTER: Jia WL 

PROVIDER: S-EPMC11197142 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature