1-Naphthylacetic acid appended amino acids-based hydrogels: probing of the supramolecular catalysis of ester hydrolysis reaction.

ABSTRACT: A 1-naphthaleneacetic acid-appended phenylalanine-derivative (Nap-F) forms a stable hydrogel with a minimum gelation concentration (MGC) of 0.7% w/v (21 mM) in phosphate buffer of pH 7.4. Interestingly, Nap-F produces two-component [Nap-F + H = Nap-F_H, Nap-F + K = Nap-F_K and Nap-F + R = Nap-F_R], three-component [Nap-F + H + K = Nap-F_H-K, Nap-F + H + R = Nap-F_H-R and Nap-F + K + R = Nap-F_K-R] and four-component [Nap-F + H + K + R = Nap-F_H-K-R] hydrogels in water with all three natural basic amino acids (H = histidine, K = lysine and R = arginine) at various combinations below its MGC. Nap-F-hydrogel forms a nice entangled nanofibrillar network structure as evidenced by field emission scanning electron microscopy (F

SUBMITTER: Bassan R 

PROVIDER: S-EPMC11197428 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature