Side-view optical microscopy-assisted atomic force microscopy for thickness-dependent nanobiomechanics.

ABSTRACT: The mechanical properties of biomaterials play an important role in regulating life processes, and thus accurately delineating the mechanical properties of biomaterials is critical to understand their functionality. Particularly, atomic force microscopy (AFM) has become a powerful and standard tool for characterizing and analyzing the nanomechanical properties of biomaterials, and providing a capability to visualize the thickness of the specimen during AFM-based force spectroscopy experiments benefits the biomedical applications of AFM. Here, we present a study of side-view optical microscopy-assisted AFM based on the integration of AFM and a detachable side-view optical microscopy module, which is able to image in real time the AFM indentation process from the side-view perspective and co

SUBMITTER: Yang Y 

PROVIDER: S-EPMC11197429 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature