Reprogramming of phytopathogen transcriptome by a non-bactericidal pesticide residue alleviates its virulence in rice.

ABSTRACT: Bacteria equipped with virulence systems based on highly bioactive small molecules can circumvent their host's defense mechanisms. Pathogens employing this strategy are currently threatening global rice production. In the present study, variations in the virulence of the highly destructive Burkholderia plantarii were observed in different rice-producing regions. The environment-linked variation was not attributable to any known host-related or external factors. Co-occurrence analyses indicated a connection between reduced virulence and 5-Amino-1,3,4-thiadiazole-2-thiol (ATT), a non-bactericidal organic compound. ATT, which accumulates in rice plants during metabolization of specific agrochemicals, was found to reduce virulence factor secretion by B. plantarii up to 88.8% and

SUBMITTER: Matsumoto H 

PROVIDER: S-EPMC11197535 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature