RiboGraph: an interactive visualization system for ribosome profiling data at read length resolution.

ABSTRACT:

Motivation

Ribosome profiling is a widely-used technique for measuring ribosome occupancy at nucleotide resolution. However, the need to analyze this data at nucleotide resolution introduces unique challenges in data visualization and analyses.

Results

In this study, we introduce RiboGraph, a dedicated visualization tool designed to work with .ribo files, a specialized and efficient format for ribosome occupancy data. Unlike existing solutions that rely on large alignment files and time-consuming preprocessing steps, RiboGraph operates on a purpose designed compact file type. This efficiency allows for interactive, real-time visualization at ribosome-protected fragment length resolution. By providing an integrated toolset, RiboGraph empowers researchers to conduct comprehens

SUBMITTER: Chacko J 

PROVIDER: S-EPMC11197854 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature