Gut microbial features and dietary fiber intake predict gut microbiota response to resistant starch supplementation.

ABSTRACT: Resistant starch (RS) consumption can have beneficial effects on metabolic health, but the response, in terms of effects on the gut microbiota and host physiology, varies between individuals. Factors predicting the response to RS are not yet established and would be useful for developing precision nutrition approaches that maximize the benefits of dietary fiber intake. We sought to identify predictors of gut microbiota response to RS supplementation. We enrolled 76 healthy adults into a 7-week crossover study with 59 individuals completing the study. Participants consumed RS type 2 (RS2), RS type 4 (RS4), and digestible starch, for 10 d each with 5-d washout periods in between. We collected fecal and saliva samples and food records during each treatment period. We performed 16S rRNA gene s

SUBMITTER: Devarakonda SLS 

PROVIDER: S-EPMC11197919 | biostudies-literature | 2024 Jan-Dec

REPOSITORIES: biostudies-literature