Nontraditional Risk Markers for Incident Coronary Artery Calcium Among Persons ≥65 Years of Age.

ABSTRACT:

Background

The initiation of coronary artery calcium (CAC) is an important physiologic milestone associated with increased cardiovascular disease risk. However, traditional risk factors (RF) do not perform well for predicting incident CAC among the 54 million older U.S. adults.

Objectives

The authors sought to assess the association between nontraditional cardiovascular disease RF and incident CAC in older persons.

Methods

There were 815 MESA (Multi-Ethnic Study of Atherosclerosis) participants ≥65 years of age who had CAC = 0 at Visit 1 and a follow-up CAC scan. Multivariable adjusted Cox hazards ratios (aHR) and C-statistics were calculated to examine the association of nontraditional RF with incident CAC.

Results

The mean age was 70.2 years and 67% were wome

SUBMITTER: Razavi AC 

PROVIDER: S-EPMC11198298 | biostudies-literature | 2024 Feb

REPOSITORIES: biostudies-literature