Revisiting the invasion paradox: Resistance-richness relationship is driven by augmentation and displacement trends.

ABSTRACT: Host-associated resident microbiota can protect their host from pathogens-a community-level trait called colonization resistance. The effect of the diversity of the resident community in previous studies has shown contradictory results, with higher diversity either strengthening or weakening colonization resistance. To control the confounding factors that may lead to such contradictions, we use mathematical simulations with a focus on species interactions and their impact on colonization resistance. We use a mediator-explicit model that accounts for metabolite-mediated interactions to perform in silico invasion experiments. We show that the relationship between colonization resistance and species richness of the resident community is not monotonic because it depends on two underlying trend

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC11198907 | biostudies-literature | 2024 Jun

REPOSITORIES: biostudies-literature