Impact of seasonal blood pressure changes on visit-to-visit blood pressure variability and related cardiovascular outcomes.

ABSTRACT:

Background

Visit-to-visit blood pressure (BP) variability associates with an increased risk of cardiovascular events. We investigated the role of seasonal BP modifications on the magnitude of BP variability and its impact on cardiovascular risk.

Methods

In 25 390 patients included in the ONTARGET and TRANSCEND trials, the on-treatment systolic (S) BP values obtained by five visits during the first two years of the trials were grouped according to the month in which they were obtained. SBP differences between winter and summer months were calculated for BP variability quintiles (Qs), as quantified by the coefficient of variation (CV) of on-treatment mean SBP from the five visits. The relationship of BP variability with the risk of cardiovascular events and mortality was asses

SUBMITTER: Mancia G 

PROVIDER: S-EPMC11198955 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature