Real-World Effectiveness of Biologics in Patients With Severe Asthma: Analysis of the KoSAR.

ABSTRACT:

Purpose

Severe asthma is associated with high morbidity and healthcare utilization; however, treatment options for these patients are limited. This study aimed to determine the therapeutic effects of biologics in clinical practice.

Methods

This multicenter, retrospective cohort study included 136 patients who received biologics for at least 4 months between September 2017 and July 2022 at 25 medical centers affiliated with the Korean Severe Asthma Registry (KoSAR). The study evaluated the treatment effects, including acute exacerbation rates, maintenance of oral corticosteroid dosages, lung function, quality of life, blood eosinophil count, and fractional exhaled nitric oxide (FeNO) levels, by comparing measurements before and after 4 months of biologic treatment. Responses

SUBMITTER: Park SY 

PROVIDER: S-EPMC11199155 | biostudies-literature | 2024 May

REPOSITORIES: biostudies-literature