Beam narrowing test: a motor index of post-stroke motor evaluation in an aged rat model of cerebral ischemia.

ABSTRACT: Each year, 15 million people worldwide suffer from strokes. Consequently, researchers face increasing pressure to develop reliable behavioural tests for assessing functional recovery after a stroke. Our aim was to establish a new motor performance index that can be used to evaluate post-stroke recovery in both young and aged animals. Furthermore, we validate the proposed procedure and recommend the necessary number of animals for experimental stroke studies. Young (n = 20) and aged (n = 27) Sprague-Dawley rats were randomly assigned to receive either sham or stroke surgery. The newly proposed performance index was calculated for the post-stroke acute, subacute and chronic phases. The advantage of using our test over current tests lies in the fact that the newly proposed motor index test ev

SUBMITTER: Pinosanu LR 

PROVIDER: S-EPMC11199207 | biostudies-literature | 2024 Jul

REPOSITORIES: biostudies-literature